Most of what we know from neuroscience studies today is based on data deriving from group averages. This can be a problem. Why?
#MRI #challenges #scicomm #sciart #scitoons #cartoons #thread
- People are like sushi! Similar in some regards, different in others.
- Common group analyses are based on group averages that discount individual variability & have reduced predictive power
- Even within groups of people with shared characteristics, no 2 individuals are alike
Our new #scicomm poster tries to explain one of neuroscience big challenge of using group averages in easy/fun terms. Inputs/Feedback appreciated! #openscience #openscicomm #opencartoons
Do you want to know more? Recommended readings/Scientific references:
Fisher, A. J., Medaglia, J. D., & Jeronimus, B. F. (2018). Lack of group-to-individual generalizability is a threat to human subjects research. Proceedings of the National Academy of Sciences, 201711978.
Foulkes, L., & Blakemore, S. J. (2018). Studying individual differences in human adolescent brain development. Nature neuroscience, 1.
Insel, T. R. (2014). The NIMH research domain criteria (RDoC) project: precision medicine for psychiatry. American Journal of Psychiatry, 171(4), 395-397.
Gordon, E. M., Laumann, T. O., Gilmore, A. W., Newbold, D. J., Greene, D. J., Berg, J. J., … & Dosenbach, N.U.F. (2017). Precision functional mapping of individual human brains. Neuron, 95(4), 791-807.